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Dr. John Burk - Presentations, Publications, and Clinical Trials

Presentations:

1. "Auto-CPAP in the Treatment of Obstructive Sleep Apnea," Mid West Association of Polysomnographic Technologists, Rosemont, Illinois, November 10, 1995.

2. "Auto-CPAP in the Treatment of CPAP-Using Obstructive Sleep Apnea Patients," International Scientific Assembly of the American College of Chest Physicians, 61st Annual Meeting, New York, New York, October 29-November 2, 1995.

3. "Indications and Considerations for Auto-CPAP Therapy," Association of Polysomnographic Technologists, Nashville, Tennessee, June 1995.

4. "Auto-CPAP (APAP) in the Treatment of Obstructive Sleep Apnea," European Respiratory Society, Nice, France, October 1994.

5. "Auto-CPAP in the Initial Treatment of Obstructive Sleep Apnea (OSA) Patients," Association of Professional Sleep Societies, Seventh Annual Meeting, Los Angeles, California, June 1993.

6. "Auto-CPAP in the Initial Treatment of Obstructive Sleep Apnea (OSA) Patients," Advances in Sleep Medicine, Winter Meeting, February 1993.

7. "Auto-CPAP in the Treatment of Obstructive Sleep Apnea: A New Approach," Association of Professional Sleep Societies, Phoenix, Arizona, June 1992.

8. "Auto-CPAP in the Treatment of Obstructive Sleep Apnea: A New Approach," Advances in Sleep Medicine, Winter Meeting, February 1992.

9. "Who Should Have Sleep Studies?" Texas Medical Association Annual Meeting, May 1989.

10. "Epidemiology of Nursery Exposure to Tuberculosis," American College of Chest Physicians, November 1977.

11. "Consecutive Cases of Fiberoptic Transbronchial Pulmonary Biopsy," KOPPA Conference, Hunt, Texas, August 1976; presented with R. L. Ragsdale and J. Robertson.

12. "Hypertension Control: Where Do We Stand Now in Alabama?" CIBA Symposium, Birmingham, Alabama, November 1975.

Publications:

13. Burk, John R: Automatic CPAP: The Next Generation. RT Magazine, June/July 1999, pages 37-42.

14. Lucas EA, Behbehani K, Bradshaw CM, Burk JR, Knaur S, Wexler DM: Comparison of Continuous Positive Airway Pressure (CPAP) to AutoCPAP* (APAP) in the Diagnosis and Treatment of Obstructive Sleep Apnea. Sleep, Volume 21, Number 3, Supplement, 1998, page 106.

15. Yen FC, Behbehani K, Lucas EA, Burk JR, Axe JR: A Noninvasive Technique for Detecting Obstructive and Central Sleep Apnea. IEEE Transactions on Biomedical Engineering, Volume 44, Number 12, December 1997, pp 1262-1268.

16. Behbehani KR, Becker PM, Burk JR, Jamieson AO, Jewell CE, Knaur SL, Lucas EA, Shehadeh F and Smith ML: ABSTRACT: Hours of Use Is Increased and Mean Therapeutic Pressure Is Reduced by Auto CPAP (APAP) Therapy in CPAP Treated Obstructive Sleep Apnea Patients. Sleep Research, Volume 26, page 326, Chase MH, Rosenthal LD, O'Connor C, eds. 1997.

17. Smith ML, Becker PM, Behbehani K, Burk JR, Jamieson AO, Jewell CE, Knaur SL, Lucas EA and Shehadeh F: ABSTRACT: Comparison of Auto CPAP (APAP) and Fixed CPAP Therapy on Nocturnal Blood Pressure Changes in Patients with Obstructive Sleep Apnea. Sleep Research, Volume 26, page 511, Chase MH, Rosenthal LD, O'Connor C, eds. 1997.

18. Behbehani KR, Lopez F, Yen F-C, Lucas EA, Burk JR, Axe JP, Kamangar F: Pharyngeal Wall Vibration Detection Using an Artifical Neural Network. Medical & Biological Engineering & Computing, Volume 35, May 1997, pp 193-198.

19. Behbehani KR, Yen F-C, Burk JR, Lucas EA, Axe JR: Automatic Control of Airway Pressure for Treatment of Obstructive Sleep Apnea. IEEE Transactions on Biomedical Engineering, Volume 42, Number 10, October 1995, pp 1007-1016.

20. Creticos P, Burk JR, Smith L, Comp R, Norman P, Findlay S: The Use of Twice Daily Nedocromil Sodium in the Treatment of Asthma. Journal of Clinical Immunology, April 1995.

21. Burk JR: Community Ethics Conference Report. Tarrant County Physician, Volume 66, Number 4, April 1994, p 35.

22. Burk JR: Camp El Tesoro de la Vida. Tarrant County Physician, Volume 62, Number 6, June 1990, p 33.

23. Wooten V, Lucas EA, Burk JR: Positive Nasal Airway Pressure Eliminates Snoring As Well As Obstructive Sleep Apnea. Pulmonary Disease Review, Volume 6, 1986, pp 575-583.

24. Burk JR, Viroslav J, Bynum LJ: Miliary Tuberculosis Diagnosed by Fiberoptic Bronchoscopy and Transbronchial Biopsy. Tubercle, Volume 59, 1978, pp 107-109.

25. Burk JR, Bahar D, Wolf FS, Greene J, Bailey WC: Nursery Exposure of 528 Newborns to Nurse with Tuberculosis. The Southern Medical Journal, Volume 71, Number 1, January 1978, pp 7-10.

26. Burk JR, Lertora JJL, Maetinex IM, Fisher JW: Renal Cell Carcinoma with Erythrocytosis and Elevated Erythropoietic Stimulatory Activity. The Southern Medical Journal, Volume 70, Number 8, August 1977.

27. Burk JR: Hypertension Control: Where Do We Stand Now in Alabama? the Journal of the Medical Association of the State of Alabama, Volume 45, Number 9, March 1976, pp 26-28.

28. Burk JR, Snow R, Sellers C, Hicks A, Maetz M, Atkins R, Lindsey HS: St. Louis Encephalitis in Jefferson County-1974: What Does the Future Hold? The Journal of the Medical Association of the State of Alabama, Volume 44, Number 12, June 1975, pp 693-697.

29. Burk JR, Lehman HF, Wolf FS: Inadequacy of Papanicolaou Smears in the Detection of Endometrial Cancer. The New England Journal of Medicine, Volume 291, Number 4, July 25, 1974, pp 191, 192.

Clinical Trials:

"Auto-CPAP With and Without a Humidifier." Study 1CA5052, Respironics, Inc., April 1995 to December 1996, Principle Investigator.

"A Multicenter Study for the Correlation Between the Findings of Atypical/Malignant Cells in Sputum and Fluorescent Bronchoscopy Using the LIFE Imaging System and White Light Bronchoscopy." Protocol LS01, Xillix Technologies Corporation, June 1994 (ongoing at this time), Principal Investigator.

"A Multicenter, Prospective Survey to Evaluate Purulent Lower Respiratory Tract Exacerbations in the Outpatient Setting." Study Z0556n, Genentech, Incorporated, July 1995, Co-Investigator.

"Real-Time Non-Invasive Method for Estimating Upper Airway Impedance of Apnea Patient During Sleep." December 1994 to December 1996, Principal Investigator.

"A Multinational, Multicenter, Double-blind, Placebo-Controlled Phase III Study to Evaluate the Efficacy and Safety of Aerosolized Recombinant Human DNase I in Hospitalized Patients with Chronic Obstructive Pulmonary Disease Experiencing a Pulmonary Exacerbation." August 1994 to September 1995, Principal Investigator.

"Enhanced CPAP Therapy for Obstructive Sleep Apnea." Study 1 R15 HL46467-01A1, National Institutes of Health and the University of Texas at Arlington, September 1992 to August 31, 1994, Co-Investigator. "A Microprocessor-Controlled Continuous Positive Airway Pressure System for Treating Obstructive Respiratory Impairments in Sleep." January 1992 to September 1995, Co-Investigator.

"Prospective, Controlled, Third Party-Blind, Randomized Study Comparing the Efficacy and Safety of IV/PO Ciprofloxacin (400/500 mg q.12h.) with Parenteral IV or IM Ceftriaxone (1000 mg q.24h.) in the Treatment of Patients with Pneumonia (Multi-Center)." Study D89-027, Miles, Inc., Pharmaceutical Division, November 1990, Principal Investigator.

"Prospective, Controlled, Randomized Study Comparing the Efficacy and Safety of Intravenous Ciprofloxacin with Standard Antibiotic Therapy in the Treatment of Selected Tissue Infections (Multi-Center)." Study D90-034, Miles, Inc., Pharmaceutical Division, November 1990, Co-Investigator.

"The Effect of Zolpidem in Elderly Patients with Chronic Insomnia." Study LSH-21, Lorex Pharmaceuticals, January 1990, Principal Investigator. "Cefaclor A.F. vs. Cefaclor in Various Bacterial Infections." Study B3M-M-AIKA, Eli Lilly & Company, January 1989, Co-Investigator.

"Development of a Microprocessor-Based Sleep Apnea Ventilator." Project #1805, Texas Higher Education Coordination Board and the University of Texas at Arlington, June 1, 1988 to August 31, 1991, Co-Investigator. "A Comparison of the Efficacy and Tolerance of Ventolin in Solution for Inhalation to Alupent Inhalant Solution to Placebo in Home Nebulization in Adults with Chronic Obstructive Pulmonary Disease." Glaxo Pharmaceuticals, April 1988, Principal Investigator.

"A Comparative Study of the Long Term Safety Profile of Estazolam, Triazolam, and Placebo in Adults with Insomnia." Abbott Laboratories, 1987-1988, Co-Investigator.

"A Double-Blind Multicenter Group Comparative Study of the Efficacy and Safety of Tilade b.i.d. (Nedocromil Sodium) vs. Placebo in the Management of Adults with Reversible Airway Obstruction." Study 87-11A, Fisons, November 1987, Principal Investigator.

"A Comparative Patient Preference Study of Two Actuators for Ventolin Inhalers." Study SAL-508-3, Glaxo Pharmaceuticals, June 1987, Principal Investigator.

"Compassionate Use of Ciprofloxacin in the Treatment of a Patient With an Infection Refractory to Currently Marketed Antibiotics." Study U86-006-96, Miles Laboratories, August 1986, Co-Investigator.

"A Comparative Study of the Side Effect Profile of Estazolam, Flurazepam, Temazepam, Triazolam, and Placebo in Adult Patients Complaining of Insomnia." Protocol M84-051, Abbott Laboratories, 1986, Co-investigator.


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